This repository contains the Markdown-based source files for the course website of BME307 – Human Molecular Genetics, taught at the University of Zurich.
The website is available at:
👉 https://peterresutik.github.io/bme307
General Overview
This course focuses on the analysis of gut microbiomes in healthy subjects and in patients with inflammatory bowel disease (IBD). The composition of gut microbiomes is investigated through typisation of 16S rRNA genes. Analyses of microbial diversity within and across samples, as well as exploratory supervised classification, are carried out using bioinformatics tools. Inflammation in the gut is assessed via histology and Western blotting of marker proteins.
ECTS Credits: 6
Registration
Students must register for block courses at:
👉 www.mybioportal.uzh.ch
Priority is given to students of the biomedicine program.
By the end of the module, students should be able to:
- Provide an overview of how the microbiome is involved in health and disease
- Describe the interactions and interdependencies of microbial communities in humans
- Outline the contribution of bacterial taxa in influencing the development of inflammatory diseases
- Apply wet-lab assays and bioinformatics tools to assess microbial diversity and disease severity
- Carry out basic analyses of microbial diversity using bioinformatics tools
Key Skills
Students will gain experience in:
- Explaining the utility of 16S rRNA gene sequencing for clinical applications
- Delineating analytical methods used to explore microbiome diversity
- Presenting results in a scientific poster format
- Language: English-friendly
- Module Coordinator: Prof. Thierry Hennet
- Bioinformatics Section Lecturer: Dr. Natasha Arora